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1.
Eur Heart J ; 42(4): 292-293, 2021 01 21.
Article in English | MEDLINE | ID: covidwho-916910

Subject(s)
Blood Donors , Humans
3.
J Surg Oncol ; 123(5): 1188-1198, 2021 Apr.
Article in English | MEDLINE | ID: covidwho-1085664

ABSTRACT

BACKGROUND: Coronavirus disease 2019 (COVID-19) has impacted cancer care globally. The aim of this study is to analyze the impact of COVID-19 on cancer healthcare from the perspective of patients with cancer. METHODS: A cross-sectional survey was conducted between June 19, 2020, to August 7, 2020, using a questionnaire designed by patients awaiting cancer surgery. We examined the impact of COVID-19 on five domains (financial status, healthcare access, stress, anxiety, and depression) and their relationship with various patient-related variables. Factors likely to determine the influence of COVID-19 on patient care were analyzed. RESULTS: A significant adverse impact was noted in all five domains (p = < 0.05), with the maximal impact felt in the domain of financial status followed by healthcare access. Patients with income levels of INR < 35 K (adjusted odds ratio [AOR] = 1.61, p < 0.05), and 35K- 100 K (AOR = 1.96, p < 0.05), married patients (AOR = 3.30, p < 0.05), and rural patients (AOR = 2.82, p < 0.05) experienced the most adverse COVID-19-related impact. CONCLUSION: Delivering quality cancer care in low to middle-income countries is a challenge even in normal times. During this pandemic, deficiencies in this fragile healthcare delivery system were exacerbated. Identification of vulnerable groups of patients and strategic utilization of available resources becomes even more important during global catastrophes, such as the current COVID-19 pandemic. Further work is required in these avenues to not only address the current pandemic but also any potential future crises.


Subject(s)
COVID-19/epidemiology , Neoplasms/surgery , Adolescent , Adult , Aged , COVID-19/psychology , Cross-Sectional Studies , Female , Humans , India/epidemiology , Male , Middle Aged , Neoplasms/psychology , Poverty , Surgical Oncology/standards , Surveys and Questionnaires , Young Adult
4.
J Surg Oncol ; 123(5): 1177-1187, 2021 Apr.
Article in English | MEDLINE | ID: covidwho-1074349

ABSTRACT

BACKGROUND: The novel coronavirus pandemic (COVID-19) hinders the treatment of non-COVID illnesses like cancer, which may be pronounced in lower-middle-income countries. METHODS: This retrospective cohort study audited the performance of a tertiary care surgical oncology department at an academic hospital in India during the first six months of the pandemic. Difficulties faced by patients, COVID-19-related incidents (preventable cases of hospital transmission), and modifications in practice were recorded. RESULTS: From April to September 2020, outpatient consultations, inpatient admissions, and chemotherapy unit functioning reduced by 62%, 58%, and 56%, respectively, compared to the same period the previous year. Major surgeries dropped by 31% with a decrease across all sites, but an increase in head and neck cancers (p = .012, absolute difference 8%, 95% confidence interval [CI]: 1.75% - 14.12%). Postoperative complications were similar (p = .593, 95% CI: -2.61% - 4.87%). Inability to keep a surgical appointment was primarily due to apprehension of infection (52%) or arranging finances (49%). Two COVID-19-related incidents resulted in infecting 27 persons. Fifteen instances of possible COVID-19-related mishaps were averted. CONCLUSIONS: We observed a decrease in the operations of the department without any adverse impact in postoperative outcomes. While challenging, treating cancer adequately during COVID-19 can be accomplished by adequate screening and testing, and religiously following the prevention guidelines.


Subject(s)
COVID-19/epidemiology , Hospitals, University/statistics & numerical data , Neoplasms/surgery , Surgical Oncology/statistics & numerical data , Cohort Studies , Humans , India/epidemiology , Infection Control/methods , Infectious Disease Transmission, Patient-to-Professional/prevention & control , Pandemics , Poverty , Retrospective Studies , Surgical Oncology/methods
5.
Indian J Cancer ; 57(4): 481-484, 2020.
Article in English | MEDLINE | ID: covidwho-881410

ABSTRACT

Worldwide, hospitals are facing problems in managing cancer patients during the ongoing COVID-19 pandemic. Given the immense cancer burden of oral cancer in India, scheduling surgeries are becoming increasingly difficult. Upfront surgeries are recommended for curative treatment of oral cancers and postponing them raises the fear of progression. Metronomic chemotherapy can be considered during the waiting period given its potential oncological benefits and ease of administration without much toxicity.


Subject(s)
Antineoplastic Combined Chemotherapy Protocols/therapeutic use , Coronavirus Infections/complications , Mouth Neoplasms/drug therapy , Pandemics , Pneumonia, Viral/complications , Administration, Metronomic , Antineoplastic Combined Chemotherapy Protocols/supply & distribution , COVID-19 , Coronavirus Infections/epidemiology , Coronavirus Infections/virology , Humans , India/epidemiology , Mouth Neoplasms/complications , Mouth Neoplasms/epidemiology , Mouth Neoplasms/virology , Oral Surgical Procedures , Pneumonia, Viral/epidemiology , Pneumonia, Viral/virology
6.
Indian J Surg Oncol ; 11(Suppl 2): 313-317, 2020 Sep.
Article in English | MEDLINE | ID: covidwho-802663

ABSTRACT

The current COVID 19 pandemic has a major impact on healthcare delivery globally. Oral cancer involving anterior arch of mandible is difficult to reconstruct and ideally, requires free fibular osteomyocutaneous flap. During this time of resource constraint situation, these free flaps are not a great choice, as it increases exposure of both patient and surgical team to the deadly virus. We are describing a novel method of reconstruction after resection of oral cancer involving anterior arch of mandible. In this new technique, we have reconstructed central arch defect by hanging bipaddle pectoralis major myocutaneous flap with orbicularis oris muscle using ethylene terephthalate suture. Operative time, early postoperative complications and early cosmetic and functional outcome were assessed. We have used this novel technique in eight patients of T4a oral cancer involving anterior arch of mandible and skin over chin. Mean operative time was 180 min. One patient had minor flap loss with surgical site infection (Clavien-Dindo grade I). In all patients, we were able to discharge all patients on eighth postoperative day. Cosmetic outcome and functional outcomes were mostly satisfactory. All patients were able to oppose their lips without any oral incompetence and drooling. Tongue mobility was good. There was no incidence of 'Andy Gump deformity'. This is a feasible option for reconstructing anterior arch defect in resource- and time-limited setting of COVID 19 pandemic. This technique can also be used in comorbid conditions where it is not advisable to do very long surgery.

7.
Indian J Anaesth ; 64(Suppl 2): S97-S102, 2020 May.
Article in English | MEDLINE | ID: covidwho-710391

ABSTRACT

Coronavirus disease 2019 (COVID-19) has gripped the world and is evolving day by day with deaths every hour. Being immunocompromised, cancer patients are more susceptible to contract the infection. Onco-surgeries on such immunocompromised patients have an increased risk of infection of COVID-19 to patients and health care workers. The society of Onco-Anesthesia and Perioperative Care (SOAPC) thereby came out with an advisory for safe perioperative management of cancer surgery during this challenging time of the COVID-19 pandemic.

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